Qap (Anatomical Pathology) 

QAP Peer Review

AP208
Case History: Hydrops fetalia, IUD at 23 weeks of gestation. Placenta.
Intended diagnosis: Parvovirus infection. Contributed by:KFT
Code Diagnosis Comment Score
anonymous Parvovirus infection (100%) May be confirmed with in-situ hybridization for Parvovirus B19.  100
anonymous Placenta: Sickle cell disease nil  0
anonymous Parvovirus B19 infection (100%) Confirm with maternal antibodies (IgG, IgM) or any other molecular studies e.g. PCR, ISH. EM to examine viral particles.  100
anonymous Parvovirus infection confirm by immunohistochemical studies or in-situ hybridization for parvovirus B19.  100
anonymous Parvovirus infection. 100% Parvovirus B19 infection can be confirmed by immunostain, in-situ hybridization or PCR. Other specials stains can be performed to look for other infective agents eg immunostain for cytomegalovirus, and Warthin-Starry stain for spirochaetes.  100
anonymous Parvovirus B19 infection. (100%) nil  100
anonymous Placenta - Parvovirus B19 infection nil  100
anonymous Parvovirus infection (100%) Perform immunostaining for confirmation  100
anonymous Parvovirus B19 infection 100% nil  100
anonymous Placental hydrop with several erythroblasts of which contains pale eosinophilic intranuclear inclusion, suggestive of Parvovirus infection. To confirm by Immunohistochemistry, serology and if possible, electromicroscopy.  100
anonymous PLACENTA - PARVOVIRUS INFECTION (100%) nil  100
anonymous Parvovirus B19 infection of fetus nil  100
anonymous Parvovirus infection evident by viral inclusion in erythroblasts, correlation with maternal serology suggested. 100% nil  100
anonymous Viral infection, suggestive of Parvovirus (100%) Check serology for raised antibody level  100
anonymous Parvovirus infection nil  100