Code |
Diagnosis |
Comment |
Score |
anonymous |
Malignant small round cell tumour. (100%). Differential diagnoses include small cell carcinoma, Merkel cell carcinoma and hematolymphoid malignancy.
|
Immunostains for CK, CK20, synaptophysin, B & T-cell markers, TdT.
|
100 |
anonymous |
small cell carcinoma
|
nil
|
100 |
anonymous |
Neuroendocrine carcinoma (grade 3, W.H.O.) 90%.
Poorly differentiated carcinoma, high grade. 10%
|
To be confirmed by immunohistochemical stains for synaptophysin, chromogranin, CD56, cytokeratin.
|
100 |
anonymous |
Small cell carcinoma
|
nil
|
100 |
anonymous |
Small cell carcinoma.
|
Confirm by chromogranin+, synaptophysin+, CK+ (perinuclear dots), LCA-.
|
100 |
anonymous |
Small cell neuroendocrine carcinoma.(100%)
|
nil
|
100 |
anonymous |
Anal polyp - Carcinoma 100% (favor small cell CA/neuroendocrine carcinoma)
|
Immunostains with keratin and neuroendocrine markers for confirmation
|
100 |
anonymous |
Neuroendocrine carcinoma 90%, malignant melanoma 10%
|
Immunostaining for neuroendocrine markers (synaptophysin, chromogranin) positive for neuroendocrine carcinoma), S-100 protein and HMB45 (positive for malignant melanoma).
|
100 |
anonymous |
Poorly differentiated neuroendocrine carcinoma. 100%.
|
Differential diagnoses include other poorly differentiated carcinoma and high grade lymphoma. Immunohistochemical studies, including epithelial markers (like Cam 5.2), chromogranin, synaptophysin, NSE, etc, are advised to confirm the diagnosis. LCA may help to exclude a high grade lymphoma.
|
100 |
anonymous |
Neuroendocrine carcinoma, small cell type.
|
nil
|
100 |
anonymous |
ANUS - SMALL CELL (NEUROENDOCRINE) CARCINOMA
|
nil
|
100 |
anonymous |
Malignant tumor, in favor of neuroendocrine carcinoma. (Please see comment for differential diagnosis)
|
Differential diagnosis includes hematolymphoid malignancy, small cell variant of malignant melanoma and Ewing sarcoma/PNET. A panel of immunohistochemical stains is needed for definitive diagnosis. They include AE11/3, synaptophysin, chromogranin, leucocyte common antigen, MPO, HMB45, S-100, CD99 and FLi1 stain.
|
100 |
anonymous |
Poorly differentiated neuroendocrine carcinoma (small cell type)
|
nil
|
100 |
anonymous |
small cell carcinoma (100%)
|
nil
|
100 |
anonymous |
Small round cell tumour , favour poorly differentiated carcinoma, need to rule out neuroendocrine carcinoma, perform chromogranin, synaptophysin, CD56 (100% Probability)
|
nil
|
100 |
anonymous |
Malignant small round cell tumour, favour small cell carcinoma (80%). Differential diagnoses include Merkel cell carcinoma (10%) and malignant melanoma (10%).
|
Immunostaining for cytokeratin, neuroendocrine markers (synaptophysin, chromogranin), CK20 and S-100 protein to help establish the diagnosis.
|
100 |