Qap (Anatomical Pathology) 

QAP Peer Review

AP173
Case History: M/23 Cervical lymph node
Intended diagnosis: Syncytial variant of nodular sclerosis Hodgkin's lymphoma. Contributed by:PKH
Code Diagnosis Comment Score
anonymous Hodgkin lymphoma, nodular sclerosis, grade 2 (BNLI), syncytial variant. (100%) Immunohistochemical study will show the following results: CD30 and CD15 positive, LCA negative, L26 negative or focally positive with heterogeneous staining pattern, CD3 negative.  100
anonymous Classical Hodgkin lymphoma nil  95
anonymous Cervical lymph node - Classical Hodgkin's lymphoma. In favour of nodular sclerosing subtype. Performing immunostains CD30 and CD15 to confirm.  100
anonymous Nodular Sclerosis Hodgkins lymphoma. BNLI grade 1 nil  100
anonymous NODULAR SCLEROSIS HODGKIN LYMPHOMA, syncytial variant. 100% Positivity for CD30 and CD15 etc. can be used to confirm the typing of classical Hodgkin lymphoma.  100
anonymous Classical Hodgkin lymphoma. (100%) DDx between mixed cellularity type and syncytial variant of nodular sclerosis type. Do CD30 stain to highlight Reed-Sternberg cells versus CD30 negative histiocytes.  100
anonymous Hodgkin Lymphoma, Nodular sclerosis (BNLI Grade I) 100% nil  100
anonymous Hodgkin's lymphoma, favour nodular sclerosing type, BNL grade 2; 100% Need more deeper sections or more blocks of the lymph node to look for more definitive sclerosing bands and nodules found in nodular sclerosis. Otherwise, Hodgkin's lymphoma, mixed cellularity type, has to be reconsidered.  100
anonymous Classical Hodgkin's lymphoma, nodular sclerosis type. nil  100
anonymous Hodgkin's disease (100%) nil  95
anonymous Hodgkin lymphoma 95% Other malignant neoplasm 5% Immunopanel: CD30 CD15 EMA CD20 CD3 CD45RB ALK S100 EBER  95
anonymous Classical Hodgkin lymphoma, favor nodular sclerosis type nil  100
anonymous Nodular sclerosing Hodgkin's disease, syncytial variant nil  100
anonymous Nodular sclerosis Hodgkin lymphoma, grade 2. 100% probability nil  100
anonymous Hodgkin lymphoma, nodular sclerosis subtype 100% nil  100
anonymous Hodgkin's Lymphoma, Nodular Sclerosis (100%) Confirm with immunostains (CD30, LCA, CD15, CD20, ALK1 etc)  100