Code |
Diagnosis |
Comment |
Score |
anonymous |
Schwannoma (70%). Differential diagnosis: Gastrointestinal stromal tumour, GIST (30%)
|
To perform immunostains for S100, c-kit and CD34. Schwannoma will be positive for S100 while gastrointestinal stromal tumour (GIST) will be positive for c-kit and CD34.
|
100 |
anonymous |
Gastrointestinal stromal tumor
|
Combined with tumor size and mitotic figure for malignant behavior
|
40 |
anonymous |
Spindle cell tumor consistent with Schwannoma. DDx GIST and leiomyoma.
|
Immunos to confirm schwannoma (S-100 protein +ve)
GIST (+ve C-kit +/- CD34)
Leiomyoma (Smooth muscle actin +ve)
|
100 |
anonymous |
Schwannoma
|
Confirm by immunostaining for S100. Differential diagnosis: Gastrointestinal stromal tumor (C-kit positive).
|
100 |
anonymous |
Neurilemoma 70% Gastrointestinal stromal tumor 30%.
|
Immunostains can help arrive at a definitive diagnosis.
S100 +ve in schwannoma. C-kit +ve in GIST.
|
100 |
anonymous |
Spindle cell tumor. Schwannoma needs to be considered. DDx includes GIST, smooth muscle tumor, etc. (100%)
|
Do S100 protein to support schwannoma. c-kit and CD34 for GIST; desmin and actin for smooth muscle tumor.
|
100 |
anonymous |
Stomach - Schwannoma 99% GIST 1%
|
To correlate with immunostains results of S-100 protein and c-kit
|
100 |
anonymous |
Gastrointestinal stromal tumour (GIST)(70%), Schwannoma (30%)
|
Areas of ? infarct/? hyaline change, low mitotic count in this block. Examine more blocks and correlate with the size of the tumour to determine the malignant potential. Immunohistochemistry panel : Most GIST are c-kit positive. Need to exclude other stromal tumours: S100 (positive for schwannoma), smooth muscle neoplasms are SMA and desmin positive. Cytokeratin to rule out the remote possibility of spindle cell carcinoma.
|
60 |
anonymous |
Spindle cell tumor: 1) Follicular dentritic cell tumor? 2) Peripheral nerve sheath tumor? 3) Gastrointestinal stromal tumor?
|
nil
|
50 |
anonymous |
SPINDLE CELL TUMOUR of gastric wall, morphologically suggestive of Schwannoma, differential diagnosis include Gastrointestinal stromal tumour. Require immunohistochemical staining for differential diagnosis. (100%)
|
nil
|
100 |
anonymous |
Schwannoma 75%
GIST 25%
|
S100 to confirm nerve sheath origin
c-kit, CD34 to exclude GIST
desmin to exclude leiomyoma
|
100 |
anonymous |
Gastric spindled cell tumor
|
Differential diagnoses are schwannoma and gastrointestinal stromal tumor. To be differentiated by immunohistochemical staining: S100, CD117
|
80 |
anonymous |
Gastrointestinal stroma tumor/Gastrointestinal autonomic nerve tumor
(GIST/GANT)
|
nil
|
40 |
anonymous |
Neurilemmoma.
Do S100 to confirm, also do CD117, CD34 to exclude GIST and desmin and SMA for smooth muscle tumour. Probability: 100%
|
nil
|
100 |
anonymous |
Gastrointestinal mesenchymal tumour (100%), favour Schwannoma (80%). Gastrointestinal stromal tumour (GIST) (20%)
|
Perform S100 protein immunostain to confirm schwannoma, CD117 to rule out GIST and actin to rule out smooth muscle tumour.
|
100 |
anonymous |
Neurilemmoma (50%)
Gastrointestinal stromal tumour (50%)
|
Immunohistochemical staining for S-100 protein, CD34, c-kit, SMA and desmin for definitive diagnosis.
|
80 |