Qap (Anatomical Pathology) 

QAP Peer Review

AP220
Case History: F/6, cervical lymph node
Intended diagnosis: Large cell anaplastic lymphoma, lymph node. Contributed by:USK
Code Diagnosis Comment Score
anonymous Malignant tumour, favour malignant lymphoma (100%), high grade, large cell To perform immunostains for B and T-cell markers, and also CD30 for possibility of anaplastic large cell lymphoma.  100
anonymous Anaplastic large cell lymphoma nil  100
anonymous Anaplastic large cell lymphoma. nil  100
anonymous Malignant lymphoma, favor anaplastic large cell lymphoma, 100%. Confirm by immunohistochemical studies CD3+, CD20-, CD30+, ALK-1+  90
anonymous Malignant tumor consistent with malignant lymphoma, large cell. 100% DDX icludes 1)Anaplastic large cell lymphoma 2)T cell rich B cell lymphoma 3)Diffuse large B cell lymphoma 4)Hodgkin's disease. etc. Perform lymphoma markers including ALK1 and CD30 etc. Other remote ddx: melanoma(S100+), poorly differentiated carcinoma(CK+), and lymphoblastic lymphoma.  100
anonymous Malignant non-Hodgkin lymphoma. Anaplastic large cell lymphoma.(100%) Do CD30 and ALK-1 stains to confirm diagnosis. Also LCA, CD3 and CD20 stains to complete the panel.  100
anonymous Cervical LYMPH NODE - ANAPLASTIC LARGE CELL LYMPHOMA 100% Subject to immunohistochemical workup (e.g. LCA/CD30/ALK1) for confirmation, and to exclude other non-lymphoid malignancies.  100
anonymous Anaplastic large cell lymphoma (ki-1 lymphoma) (90%), carcinoma (10%) immunostain: CD30, ALK, BCK  100
anonymous Malignant lymphoma 100% DDX: anaplastic large cell lymphoma, syncytial variant of nodular sclerosis Hodgkin's disease Suggest immunohistochemical study i.e. CD30, CD25, CD15 for further classification  100
anonymous Hematolymphoid malignancy. Differential diagnosis: 1. Anaplastic large cell lymphoma. 2. Diffuse large B cell lymphoma. 3. Granulocytic sarcoma. Need IHC - CD30, ALK, MPO, CD20, CD3, EMA, CAE.  90
anonymous Anaplastic Large Cell Lymphoma I would like to perform immunostains for EMA, LCA, CD30, CD3, L26 to confirm the diagnosis. I would also do the stain for ALK because of diagnostic and prognostic significance.  100
anonymous Malignant lymphoma, favor anaplastic large cell lymphoma to be confirmed by immunostaining: CD30+, ALK may be positive, EMA+  100
anonymous anaplastic large cell lymphoma. Probability: 100% nil  100
anonymous Anaplastic Large Cell lymphoma. 100% ALK-1 stain  100
anonymous Anaplastic large cell lymphoma (100%) Immunostaining with CD30, ALK, EMA, CD3, CD43, CD20, AE1/AE3  100