Code |
Diagnosis |
Comment |
Score |
anonymous |
Malignant lymphoma (80%)
High grade glial tumour (20%)
|
Advise immunostains for lymphoid markers (including Ki-1) and GFAP.
|
100 |
anonymous |
High grade malignant tumour consistent with glioblastoma multiforme 100%
|
To exclude lymphoma by immunohistochemistry.
|
80 |
anonymous |
Malignant lymphoma. 100%
|
Confirm by immunohistochemical stain for lymphoid markers.
|
100 |
anonymous |
Glioblastoma multiforme (100%)
|
nil
|
50 |
anonymous |
Diffuse large cell lymphoma
|
Immunostaining for LCA, L26, CD3.
|
100 |
anonymous |
GLIOBLASTOMA MULTIFORME with osteosarcoma-like area. 100%
|
The diagnosis of GBM can be confirmed by GFAP positivity.
|
50 |
anonymous |
Malignant anaplastic neoplasm. (100%)
|
DDx includes malignant lymphoma, especially anaplastic large cell lymphoma; metastatic anaplastic carcinoma; sarcoma including gliosarcoma; and unlikely malignant melanoma and germinoma. Favor malignant lymphoma. Confirm the diagnosis by a panel of immunostains including CD30, EMA and ALK-1 for anaplastic large cell lymphoma; LCA, B- & T-cell markers for other lymphomas; cytokeratins, in addition to other markers to exclude other differentiation, for carcinomas; GFAP and vimentin for glial sarcoma; S-100 protein and HMB-45 for melanoma; PLAP for germinoma.
|
70 |
anonymous |
Brain - large cell lymphoma 100%
|
To apply a panel of immunomarkers to confirm lymphoid nature and to determine lineage.
|
100 |
anonymous |
Malignant lymphoma,
- diffuse large cell 80%
- anaplastic large cell lymphoma 20%
|
Need to establish lineage by T and B markers.
Need to rule out anaplastic large cell lymphoma by CD30(Ki-1), also need to perform ALK-1 for prognostic reason.
|
100 |
anonymous |
High grade malignant neoplasm 100%
DDX: Malignant lymphoma, glioblastoma multiforme
|
Suggest immunohistochemical staining with LCA, GFAP for delineation
|
80 |
anonymous |
GLIOBLASTOMA. 100%
|
Suggest to perform immunostain for GFAP to confirm the diagnosis and cytokeratin and leuococyte common antigen to exlude carcinoma and lymphoma.
|
80 |
anonymous |
Malignant neoplasm, favour malignant lymphoma (100%)
|
Glioblastoma multiforme has been considered as a ddx.
- Can be distinguished by immunostaining: Lymphoma (LCA+ GFAP-), GBM (LCA- GFAP+)
|
100 |
anonymous |
Giant cell glioblastoma
|
nil
|
50 |
anonymous |
Malignant neoplasm.
Favor malignant lymphoma, high grade.
Probability : 100%
|
Would perform T & B marker, CD30, ALK, and S100, cytokeratin, GFAP to exclude malignant melanoma, metastatic carcinoma and glioblastoma multiforme.
|
100 |
anonymous |
Large cell lymphoma 90%
Glioblastoma multiforme 10%
|
Immunostains including LCA and GFAP to be performed to confirm or disprove the diagnosis of lymphoma or glioblastoma multiforme.
|
100 |
anonymous |
Non-Hodgkin lymphoma (80%)
Other differential diagnosis (20%) include glioblastoma multiforme and metastatic undifferentiated carcinoma.
|
Immunohistochemical stain for LCA, B & T-cell markers, cytokeratin and GFAP would be helpful.
|
100 |