Qap (Anatomical Pathology) 

QAP Peer Review

AP95
Case History: Rectal biopsy
Intended diagnosis: Adenocarcinoma of rectum. Contributed by:JKCC
Code Diagnosis Comment Score
anonymous Adenocarcinoma (100%) No comment.  100
anonymous Adenocarcinoma 100% probability  100
anonymous Adenocarcinoma. 100% Nil  100
anonymous RECTUM, biopsy : ADENOCARCINOMA. ( 100% ) The adjacent non-neoplastic rectal mucosa shows no dysplasia. A metastasis or spread from adjacent organs, e.g. prostate, should also be considered. Clinical correlation and immunocytochemistry may be necessary ( e.g. perform prostate-specific antigen ).  100
anonymous adenocarcinoma 100% no comment  100
anonymous Adenocarcinoma 100% no comment  100
anonymous Adenocarcinoma. 100% Nil.  100
anonymous Adenocarcinoma. 100% Do chromogranin and synaptophysin stains to rule out coexisting carcinoid component.  100
anonymous Severely dysplastic glands with surrounding loose myxoid stroma, suggestive of invasive adenocarcinoma 100% Ask for deeper sections and correlate with endoscopic finding  90
anonymous Suspicious of malignancy (100%) including metastasis. Metastatic prostatic adenocarcinoma should be excluded by PSA, PSAP stains.  90
anonymous Adenocarcinoma 100% nil  100
anonymous Adenocarcinoma - 100% Nil  100
anonymous Adenocarcinoma 99% Severe dysplasia/CIS 1% The features are highly suggestive of invasive carcinoma. Need correlation with endoscopic findings.  100
anonymous Rectal mucosa with high-grade dysplasia 100% A repeat biospy should be advised, because (1)the area with irregular hyperchromatic glangs and atypical mucosal cells is distorted by crush artefact, and (2) there is no muscularis mucosae to assess tumor invasion.  70
anonymous Suspicious of adenocarcinoma. Probability 100%. - Proceed to deeper sections.  90
anonymous RECTUM, biopsy - ADENOCARCINOMA (100%) Suggest immunohistochemical staining for prostate specific antigen and prostatic acid phophatase.  100