Code |
Diagnosis |
Comment |
Score |
anonymous |
Embryonal rhabdomyosarcoma (100%)
|
Immunostains for myogenin, MyoD1, desmin, actin for confirmation.
|
100 |
anonymous |
Malignant small round cell tumor (100%). Morphologic appearances most compatible with embryonal rhabdomyosarcoma.
|
Confirmation with immunostains (+ve myogenic markers - desmin, myogenin).
The panel should include other stains including CD99, a cytokeratin and S-100 protein.
|
100 |
anonymous |
Malignant small round cell tumor, 100%, favor embryonal rhabdomyosarcoma. To confirm by positive immunostaining for desmin, actin and myogenin.
|
Differential diagnoses: Ewing's sarcoma/ PNET (PAS positive, myoid markers negative); lymphoma (LCA positive)
|
100 |
anonymous |
EMBRYONAL RHABDOMYOSARCOMA. 100%
|
Skeletal muscle differentiation to be confirmed by actin, desmin, Myo-D1 etc.
|
100 |
anonymous |
Embryonal rhabdomyosarcoma. (100%)
|
Do myogenin stain to confirm.
|
100 |
anonymous |
Lacrimal gland - small round cell tumour
DDX:1) embryonal rhabdomyosarcoma 90% 2)Ewing sarcoma/PNET
|
Need ancillary tests (immunohistochemistry and/or EM) to reach definitive diagnosis
|
100 |
anonymous |
High grade malignant small round cell tumour, with differential diagnosis of
1. Rhabdomyosarcoma (90%)
2. Ewing sarcoma (10%)
|
A panel of immunostains should be performed. Desmin, myogenin and MyoD1 will be positive in rhabdomyosarcoma, CD99 will be positive in Ewing sarcoma.
|
100 |
anonymous |
Malignant small round cell tumour 100%
|
DDX includes rhabdomyosarcoma, malignant lymphoma.
Suggest immunohistochemical staining for desmin, myogenin, TdT, CD99
|
100 |
anonymous |
Small blue round cell tumor of childhood. By the age and location, Embryonal rhabdomyosarcoma.
|
Confirmed by IHC - SMA, Desmin, Calponin, Myogen, MyoD1, NSE, Synaptophysin, Chromogranin, CD99 to exclude other differential diagnosis.
|
100 |
anonymous |
LACRIMAL GLAND mass - MALIGNANT NEOPLASM, mesenchymal. (100%)
|
Differential diagnosis includes mesenchymal chondrosarcoma, rhabdomyosarcoma, PNET/Ewing's sarcoma, hemangiopericytoma and synovial sarcoma. Immunohistochemical stains need to be performed.
|
90 |
anonymous |
Malignant small round blue cell tumour 100%
|
DDx soft tissue leukaemic deposit, embryonal rhabdomyosarcoma, PNET, lymphoma
Perform immunostains:
-CD99
-desmin, actin, MyoD1 (rhabdomyosarcoma)
-CD45, MPO (leukaemia, lymphoma)
-cytokeratin (rhabdoid tumour)
-synaptophysin (PNET)
|
100 |
anonymous |
Small round cell malignancy, favor embryonal rhabdomyosarcoma
|
To perform immunostaining, including actin, desmin, myogenin etc for definitive diagnosis
|
100 |
anonymous |
Embryonal sarcoma
|
Exclude striated muscle differentiation (embryonal rhabdomyosarcoma) with desmin and muscle specific actin stains.
|
90 |
anonymous |
Primitive small round cell tumour of children, favour embryonal rhabdomyosarcoma. Probability: 100%
|
nil
|
100 |
anonymous |
Primitive small round cell tumour of children, favour embryonal rhabdomyosarcoma
|
nil
|
100 |
anonymous |
Embryonal rhabdomyosarcoma 100%
|
Confirm by immunostains for actin, desmin and MyoD1
|
100 |
anonymous |
Small round cell tumor, differential diagnosis include embryonal rhabdomyosarcoma (80%) and other SRCTs (20%, eg. Ewing/PNET, myeloid sarcoma, neuroblastoma, melanoma, myoepithelioma, synovial sarcoma etc)
|
Immunohistochemical stains for myogenin, cytokeratin, desmin, neural markers, S100 proteins, CD99, MPO, LCA, HMB45, calponin would help diagnosis. Cytogenetics for characteristic translocations are also helpful.
|
100 |