Qap (Anatomical Pathology) 

QAP Peer Review

AP196
Case History: M/71, Frontal lobe tumor.
Intended diagnosis: Chordoid meningioma. Contributed by:USK
Code Diagnosis Comment Score
anonymous Meningioma (100%), chordoid subtype Positive for EMA,varying positivity for S100 and negative for GFAP.  100
anonymous Chordoid meningioma (100%). nil  100
anonymous Meningioma, suggestive of chodoid variant (95%); Melanocytoma (5%) Immunostaining for EMA (positive in meningioma); S100 and HMB45 (positive in melanocytoma)  95
anonymous MENINGIOMA consistent with chordoid subtype 100%. Meningeal lineage to be confirmed by positivity to EMA(may be focal for this subtype).  100
anonymous Meningioma. (100%) nil  90
anonymous Chordoid meningioma, WHO grade II, 100% nil  100
anonymous Brain - Chordoid Meningioma 100% nil  100
anonymous Meningioma with microcystic pattern (WHO grade I) (100%) Extensive sampling of the tumour in order to rule out atypical features and coagulative necrosis is needed.  90
anonymous Meningioma 100% nil  90
anonymous Meningioma (Chordoid type) nil  100
anonymous MICROCYSTIC MENINGIOMA (100%) nil  90
anonymous Ependymoma 40% Meningioma 60% Correlate with CT for location (?attachment to falx) Perform immunostaining: GFAP (ependymoma) EMA/S100/desmoplakin (meningioma)  80
anonymous Meningioma, WHO grade I nil  90
anonymous Hemangioma 50% Meningioma 50% nil  50
anonymous meningioma, grade 1. Probability: 100% nil  90
anonymous Meningioma 100% Features of chordoid variant are present. Chordoid variant of meningioma (WHO grade II) shows greater likelihood of recurrence.  100
anonymous Meningioma with area of chordoid features. Chordoid features can be mixed with typical meningioma. Recurrence rate would be higher than typical meningioma. More extensive sampling of tissue and immunostain (MIB1) for proliferative activity would be useful in classification.  100