Code |
Diagnosis |
Comment |
Score |
anonymous |
Amyloidosis and ulcer (100%)
|
Section shows small intestinal wall and adhering diverticulum-like structure. Extensive mucosal ulceration is seen in the latter. Scanty atypical stromal cells are seen. Suggest investigate for Cytomegaloviral infection with immunohistochemical stain. Amyloid deposit is seen in vessel wall of small intestine. Advise Congo red stain for confirmation. Please correlate clinically and with gross finding to see if the descending colon perforation is related to the pathology mentioned above.
|
100 |
anonymous |
Amyloidosis 100%
|
The amyloid is mainly present in the vessel wall.
Presence of amyloid can be confirmed by Congo red stain and its characteristic apple green birefringence under polarised microscopy.
|
100 |
anonymous |
DESCENDING COLON : AMYLOIDOSIS; PERITONITIS consistent with PERFORATION. ( 100% )
|
Special stains including Congo red should be performed and examined under polarized light. The amyloidosis may be related to chronic renal failure or haemodialysis, however, other possibilities including myeloma should also be considered. The ulcer shows many relatively mature plasma cells with occasional binucleated forms. It is likely to be reactive in nature. However, immunocytochemistry for light chain restriction may be performed if indicated.
|
100 |
anonymous |
Amyloidosis
|
No comment.
|
100 |
anonymous |
Amyloidosis 100%, with plasma cell infiltration
|
Confirm amyloidosis with congo red stain.
Immunostaining with Kappa/Lambda light chain
to rule out plasmacytoma/myeloma
|
100 |
anonymous |
Descending colon - perforated ulcer.
Small bowel - amyloidosis.
100%
|
- Further sampling may show amyloidosis in the colon itself.
- Congo red for amyloid and immunostain for beta 2-microglobulin to confirm the nature of the deposits.
- One mechanism for amyloid-induced ulcer in the GI tract is ischaemia.
|
100 |
anonymous |
Amyloidosis. 100%
|
Confirm by Congo red stain with apple green birefrigence under polarized light.
|
100 |
anonymous |
Amyloid deposits in blood vessels with ischaemic perforation of colon 100%
|
Congo red stain for confirmation
To correlate with history (? any haemodialysis)
|
100 |
anonymous |
Amyloidosis (100%)
|
Congo Red to confirm.
|
100 |
anonymous |
Secondary amyloidosis & colonic perforation 100%
|
suggest clinical correlation with history of haemodialysis
|
100 |
anonymous |
Amyloidosis & probable cytomegalovirus infection - 100%
|
Suggest Congo red stain for amyloid & immunopeoxidase stain for CMV
|
100 |
anonymous |
Ulcer with CMV infection (inside endothelial cells) 100%
Also present are amorphous eosinophilic materials in occasional small venular wall, suggestive of amyloid (related to CRF) 100%
|
Immunohistochemical studies for further support.
Special stains (Congo Red, etc.) for amyloid.
|
100 |
anonymous |
Amyloidosis 100%
|
Immunohistochemistry may be used to
characterize the nature of the amyloid
protein, and history if hemodialysis
for chronic renal failure and high
circulating beta2-microglobulin in serum
indicate hemodialysis-associated
amyloidosis.
|
100 |
anonymous |
Amyloidosis leading to vasculopathy & bowel perforation. Probability 100%
|
- Confirm with special stains : Congo-red, crystal violet.
- Should consider whether the cause of renal failure is due to amyloidosis. If the cause of renal failure is not amyloidosis, the amyloid seen may be related to accumulation of B-2 microglobulin secondary to chronic renal failure.
|
100 |
anonymous |
INTESTINE - AMYLOIDOSIS (100%)
|
Suggest confirmation by Congo red stain.
|
100 |