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| Code | Diagnosis | Comment | Score |
| anonymous | Gastrointestinal stromal tumour (80%) Gangliocytic paraganglioma (20%) | Advise immunohistochemical stains including CD34 and c-kit (positive in GIST), and neuroendocrine markers and S100 (positive in gangliocytic paraganglioma). For GIST, this case will have at least uncertain malignant potential in view of its large size, high cellularity and cellular atypia. Advise more sampling to properly document the mitotic count, and look for features of malignancy histologically, such as mucosal invasion, and clinically. | 100 |
| anonymous | Malignant gastrointestinal stromal tumour (malignant GIST), 100% | To be confirmed with CD34 and c-kit. | 100 |
| anonymous | Gastrointestinal stromal tumor, 100% | Immunohistochemical studies and EM examination may be considered to delineate its lineage. In view of the large size of the tumor and also the presence of significant nuclear pleomorphism, this tumor has at least to be considered as having a low grade malignant potential. | 100 |
| anonymous | DUODENUM : GASTROINTESTINAL STROMAL TUMOUR (100%) | Immunohistochemical studies using CD117 (c-kit), S-100, actin and desmin may be necessary for better characterization of the tumour. The distinction between benign, borderline and malignant stromal tumours is notoriously difficult. Apart from the demonstraton of invasion of adjacent organs and metastatic spread, the most reliable guides to malignancy are site of tumour (most small intestinal tumours being malignant), size and mitotic count. Neuroendocrine tumours like carcinoid tumour may also occur in this site. However, the packeting feature which is characteristic is absent in this case. | 100 |
| anonymous | Malignant gastrointestinal stromal tumor (100%) | nil. | 100 |
| anonymous | Gastrointestinal stromal tumor (epithelioid) | Confirm by immunostaining for c-kit. Difficult to comment on malignant potential based on one section (but probably malignant due to large size). Need thorough sampling for mitotic count also. | 100 |
| anonymous | Epithelioid gastrointestinal stromal tumor, malignant. 100% | This tumor may show CD34+, c-kit+, CK- immunophenotype. | 100 |
| anonymous | DDx between neuroendocrine tumor (including gangliocytic paraganglioma) and gastrointestinal stromal tumor (including gastrointestinal autonomic nerve tumor). (100%) | Perform chromogranin and synaptophysin stains to demonstrate the neuroendocrine nature; S100 protein stain to highlight sustenticular cells in paraganglioma; CD34 and c-kit stains for gastrointestinal stromal tumor and electron microscopy for gastrointestinal autonomic nerve tumor. | 80 |
| anonymous | Malignant Gastrointestinal Stromal Tumour 100% | Immunostains ( CD117, CD34, S-100, Desmin, cytokeratin ) for supporting the diagnosis | 100 |
| anonymous | Neuroendocrine tumour (80%) Duodenal gangliocytic paraganglioma (20%) | To be confirmed by immunopositivity towards NSE, synaptophysin, chromogranin A, S-100 protein and pancreatic polypeptide. Additional blocks to rule out gangliocytic paraganglioma. | 100 |
| anonymous | Malignant gastro-intestinal stromal tumour (GIST) 100% | nil | 100 |
| anonymous | Malignant gastrointestinal stromal tumor. 100% | nil | 100 |
| anonymous | Gastrointestinal stromal tumor 100% | 1. Immunophenotypic profile: c-kit (CD117) +ve, CD34 +ve (variable) 2. EM: for possible GANT (subtype) 3. Prognosis: at least uncertain malignant potential [small intestine location, large tumour 9 cm (>4.5 cm), yet rare mitosis], need to examine more blocks. | 100 |
| anonymous | Gastrointestinal stromal tumour, category 1 (GIST) | nil | 95 |
| anonymous | DDX : Gastrointestinal stromal tumor. Paraganglioma. Probability : 100% | Would perform immunostaining for CD117 (positive in GIST), S100 highlight sustantacular cell in paraganglioma) and synaptophysin (positive in paraganglioma). | 80 |
| anonymous | Gastrointestinal stromal tumour (100%) | The tumour shows uncertain malignant potential due to its large size. Additional blocks should be examined to assess the mitotic rate. | 100 |
| anonymous | Duodenum - Gastrointestinal stromal tumour, high risk. | nil | 100 |