Code |
Diagnosis |
Comment |
Score |
anonymous |
High grade sarcoma (100%), differential diagnoses are myxofibrosarcoma and de-differentiated liposarcoma
|
Immunostains for CDK4 and p16 are positive in de-differentiated liposarcoma. MDM2 amplication can be demonstrated by FISH test in liposarcoma.
|
100 |
anonymous |
Liposarcoma
|
nil
|
50 |
anonymous |
Low grade myxoid sarcoma
|
Differential diagnosis myxofibrosarcoma or myxoid liposarcoma
|
50 |
anonymous |
Well-differentiated liposarcoma 90%
Myxofibrosarcoma 10%
|
1. Perform immunohistochemical studies or FISH for CDK4 and mdm2 to confirm well-differentiated liposarcoma;
2. Sample more blocks to look for more typical well-differentiated liposarcoma and possible de-differentiation area.
|
60 |
anonymous |
Myxoid liposarcoma
|
Unlikely ddx: sclerosing well differentiated liposarcoma should be MDM2+ and CDK4+.
Myxoid liposarcoma has t(12,16) or t(12,22) translocation.
|
50 |
anonymous |
Myxoid malignant fibrous histiocytoma (100%)
|
nil
|
100 |
anonymous |
Left lower limb tumour, DDx:
1. Myxofibrosarcoma 80%
2. Well differentiated liposarcoma 20%
|
Ensure adequate sampling for definitive diagnosis, immunohistochemistry with markers MDM2 and CDK4 to rule in/out WD liposarcoma
|
100 |
anonymous |
Sarcoma, favour myxofibrosarcoma (90%), differential diagnosis includes myxoid liposarcoma (5%) and well differentiated liposarcoma (5%)
|
extensive sampling to look for lipoblast
|
100 |
anonymous |
Myxofibrosarcoma 100%
|
nil
|
100 |
anonymous |
Dedifferentiated liposarcoma
|
nil
|
70 |
anonymous |
SOFT TISSUE tumour, left lower limb - MYXOFIBROSARCOMA
|
nil
|
100 |
anonymous |
Myxofibrosarcoma
|
nil
|
100 |
anonymous |
Soft tissue - Well differentiated liposarcoma
|
With focal pleomorphic area. Examine more blocks from tumour.
|
50 |
anonymous |
dedifferentiated liposarcoma (100%)
|
nil
|
70 |
anonymous |
low grade fibromyxoid sarcoma. 100%
|
nil
|
50 |
anonymous |
high grade sacrcoma liposarcoma
|
nil
|
60 |
anonymous |
Pleomorphic liposarcoma 100%
|
nil
|
60 |