Qap (Anatomical Pathology) 

QAP Peer Review

AP151
Case History: F44 Incidental finding of left abdominal mass (? GIST). The abdominal mass was an enlarged spleen (14x9x7 cm) with a pedunculated mass of 10x8x7 cm.
Intended diagnosis: Splenic hamartoma. Contributed by:IOLN
Code Diagnosis Comment Score
anonymous Splenic hamartoma (100%) Focal mild extramedullary haematopoiesis is noted.  100
anonymous HAMARTOMA (100%) Immunohistochemical staining may help in differentiation from hemangioma. The endothelial cells in hamartomas will be factor VIII, CD31 and CD8 positive. Hamangioma is negative for CD8.  100
anonymous Splenic hamartoma. 100% nil  100
anonymous Spenic hamartoma nil  100
anonymous LITTORAL CELL ANGIOMA. 100% nil  90
anonymous Splenic hamartoma. (100%) nil  100
anonymous Spleen - Extramedullary hemopoiesis 100% EMH is the most striking feature in the section. Hemangioma-like or peliosis-like appearance is also noted. A hematologic work-up for this patient is indicated, to rule in/out chronic myeloproliferative disorders.  60
anonymous Splenic hamartoma with extramedullary haematopoiesis (100%) nil  100
anonymous Splenic Haemangioma 100% nil  90
anonymous HAEMANGIOMA (100%) nil  90
anonymous Splenic hamartoma (100%) nil  100
anonymous Splenic hamartoma with extramedullary hematopoiesis 100% nil  100
anonymous Favour splenic hamartoma. Would perform CD8 to rule out hemangioma. 100% Probability nil  100
anonymous Splenic hamartoma 100% Association with tuberous sclerosis may be present.  100
anonymous Benign splenic lesion, 100% Differential diagnosis includes accessory spleen, haemangioma and harmatoma. The endothelial lining cells of haemangioma are negative for CD8 while those of harmatoma are positive for CD8. CD8 will also highlight the sinuses in accessory spleen.  95