Qap (Anatomical Pathology) 

QAP Peer Review

AP179
Case History: M/60, Generalized lymphadenopathy. Groin lymph node biopsy
Intended diagnosis: Angioimmunoblastic T-cell lymphoma. Contributed by:PKH
Code Diagnosis Comment Score
anonymous Angioimmunoblastic T cell lymphoma (100%) Immunostains for B and T cell markers and follicular dendritic cell marker to confirm diagnosis. Lymphoma cells will be positive for T marker. Meshworks of follicular dendritic cells will be shown.  100
anonymous Angioimmunoblastic T-cell lymphoma nil  100
anonymous Angioimmunoblastic T-cell lymphoma (100%) Confirm diagnosis by immunostains (CD2,3,4,5,7,8). Additional studies, i.e. ISH for EBER and PCR for T-cell receptor gene rearrangement may be performed.  100
anonymous Angioimmunoblastic T-cell lymphoma Confirm by immunostaining: lymphoma cells positive for T cell markers; follicular dendritic cells abundant (CD21+).  100
anonymous Angioimmunoblastic T-cell lymphoma 100%. nil  100
anonymous Angioimmunoblastic T-cell lymphoma. (100%) Confirm by doing immunostains of lymphoma panel and EBER.  100
anonymous AILD-like Anaplastic large cell lymphoma 100% To correlate with results of immunostains: T-cell and CD30 and ALK1  80
anonymous Malignant lymphoma, favour angioimmunoblastic T-cell lymphoma Perform immunohistochemical panel : CD3, CD20. Lesion cells expected to be CD3+. CD21/CD35 will show an expanded follicular dendritic cell meshwork.  100
anonymous Angioimmunoblastic T cell lymphoma nil  100
anonymous ANGIOIMMUNOBLASTIC T-CELL LYMPHOMA; confirm with immunostaining for CD3, CD4, CD8, CD20, CD21 (100%) nil  100
anonymous Angioimmunoblastic lymphadenopathy/lymphoma 100% TCR and Ig rearrangement studies for clonality and CD10 immuno to support diagnosis of lymphoma  100
anonymous Angioimmunoblastic T-cell lymphoma To be confirmed by immunohistochemistry: CD3+, L26-; might perform CD21 and CD35 to highlight follicular dendritic cell network.  100
anonymous Angioimmunoblastic T cell lymphoma nil  100
anonymous Follicular dendritic cell sarcoma, interdigitating dendritic cell sarcoma, angioimmunoblastic T-cell lymphoma. Do S100, CD21 and CD35, CD3 and CD20. Probability: 100% nil  100
anonymous Angioimmunoblastic T cell lymphoma 100% Perform T and B cell markers and CD21 to confirm T cell proliferation and follicular dendritic cell population  100
anonymous Angioimmunoblastic T cell lymphoma (90%) Follicular dendritic cell sarcoma (10%) Immunohistochemical staining for CD3, CD21, CD35 to highlight the atypical cells.  100