Qap (Anatomical Pathology) 

QAP Peer Review

AP169
Case History: F/25, breast mass
Intended diagnosis: Atypical medullary carcinoma. Contributed by:JKCC
Code Diagnosis Comment Score
anonymous Invasive ductal carcinoma, consistent with medullary carcinoma. (100%) nil  100
anonymous Breast: poorly differentiated carcinoma, morphologically favor large cell neuroendocrine carcinoma nil  10
anonymous Atypical medullary carcinoma. Young age of patient. Need to screen for BRCA1 mutation.  100
anonymous Atypical Medullary Carcinoma (to look for germline BRCA1 mutations) nil  100
anonymous MEDULLARY CARCINOMA. 100% nil  100
anonymous Medullary carcinoma of breast. (100%) nil  100
anonymous Breast - Medullary carcinoma 100% nil  100
anonymous Medullary carcinoma, 70% Invasive ductal carcinoma, 20% Metastatic carcinoma, 10% Need more blocks to look for areas of conventional invasive ductal carcinoma or features atypical of medullary carcinoma. Need to exclude the possibility of metastatic carcinoma. ER, PR, BRST-2 and CK7 positivity favour a breast primary.  100
anonymous MEDULLARY CARCINOMA OF BREAST 100% FURTHER SAMPLING TO EXCLUDE PRESENCE OF HIGH GRADE DUCTAL CARCINOMATOUS COMPONENT  100
anonymous Medullary carcinoma. nil  100
anonymous Medullary Carcinoma (100%) nil  100
anonymous Medullary carcinoma Bizarre giant cells present Adequate sampling required  100
anonymous Medullary carcinoma nil  100
anonymous Medullary carcinoma. 100% Probability nil  100
anonymous MEDULLARY CARCINOMA nil  100
anonymous Invasive ductal carcinoma of breast, grade 3 The diffeential diagnosis is medullary carcinoma of breast, a diagnosis to be made with caution, since it may deprive a patient with high grade ductal carcinoma the benefit of adjuvant therapy.  100