Code |
Diagnosis |
Comment |
Score |
anonymous |
Extramammary Paget's disease (100%)
|
Immunostains for cam 5.2, EMA and monoclonoal CEA to confirm diagnosis. Stains for melanocytic markers (S100 and HMB45) to exclude melanoma.
|
100 |
anonymous |
Bowen disease
|
nil
|
50 |
anonymous |
Frozen section diagnosis: positive for lesion, await paraffin section for definitive diagnosis. Differentials include extramammary Paget's disease and malignant melanoma.
|
Special stains to confirm Paget's (mucin, pCEA, Cam 5.2)
Immunos to rule out melanoma (S-100 protein and HMB45)
|
80 |
anonymous |
Extramammary Paget's disease
|
Confirm by immunostaining for Cam5.2 (+). Also exclude malignant melanoma (Cam5.2 negative, S100 positive) and Pagetoid Bowen's disease (Cam5.2 negative)
|
100 |
anonymous |
Suspicious cells consistent with extramammary Paget's disease. 100%
|
To correlate with clinical findings eg any underlying carcinoma such as rectal carcinoma. Immunostains: S100 to rule out melanoma. Paget's disease should be +ve for CAM5.2 and CEA.
|
100 |
anonymous |
Extramammary Paget's disease. (100%)
|
Nil.
|
100 |
anonymous |
Scrotal skin - Extramammary Paget's disease 100%
|
To be supported by positive stains for mucin and CEA.
|
100 |
anonymous |
Malignant cells in dermo-epidermal junction and dermis (100%), defer for paraffin for definitive diagnosis.
|
DD'x include 1) Extramammary Paget's disease, Bowen's disease and 3) melanocytic neoplasm. IH panel : CAM5.2 (for Paget's cells), Cytokeratins (for Bowenoid cells) and S100/HMB45 (for melanoma/melanocytic cells).
|
100 |
anonymous |
Malignant tumor: 1) extramammary Paget's disease? 2) Superficial spreading malignant melanoma?
|
nil
|
50 |
anonymous |
EXTRAMAMMARY PAGET'S DISEASE (100%)
|
nil
|
100 |
anonymous |
Paget's disease 100%
|
Cam 5.2, CK7/20 to confirm
BRST-2 to support primary appendageal origin
S100/HMB45 to exclude melanoma
LCA to exclude lymphoma
|
100 |
anonymous |
Extramammary Paget’s disease
|
Suggest excluding underlying genital malignancy
|
100 |
anonymous |
Paget’s disease, extramammary. Probability: 100%
|
nil
|
100 |
anonymous |
Extramammary Paget's disease (90%), Bowen'sdisease (10%)
|
Extramammary Paget's disease can be confirmed by performing mucin stain and immunostains for CEA and EMA; Bowen's disease is negative.
|
100 |
anonymous |
Extramammary Paget's disease (100%)
|
S-100 protein to exclude melanoma.
|
100 |