Qap (Anatomical Pathology) 

QAP Peer Review

AP224
Case History: F/51, 3 cm submandibular mass
Intended diagnosis: Solitary fibrous tumor. Contributed by:KFT
Code Diagnosis Comment Score
anonymous Solitary fibrous tumour (100%) Confirm with immunostain for CD34.  100
anonymous solitary fibrous tumor nil  100
anonymous Haemangiopericytoma (100%) IHC stain: CD34 (expected to be positive)  80
anonymous Solitary fibrous tumor (80%) Cellular capillary hemangioma (20%) Immnostaining for CD34 for solitary fibrous tumor; actin to highlight lobulation and pericytes in capillary hemangioma.  100
anonymous Solitary fibrous tumor 100%. To confirm by CD34 stain.  100
anonymous Vascular neoplasm, favors capillary hemangioma. DDx includes hemangioendothelioma and glomus type tumor.(100%) Do CD31 to confirm vascular channels. Do smooth muscle actin to exclude glomus type tumor.  40
anonymous Submandibular mass - Solitary fibrous tumour 90% - Myofibroma 10% To be differentiated by immunostaining. SFT is actin-ve.  100
anonymous Solitary fibrous tumour nil  100
anonymous SOLITARY FIBROUS TUMOUR 100% nil  100
anonymous Spindle cell tumor. Differential diagnosis: Myoepithelioma, Solitary fibrous tumor, Hemangiopericytoma. nil  80
anonymous Submandibular mass - Solitary fibrous tumour. The diagnosis can be confirmed by immunostaining for CD34. Also rule out vascular tumour and smooth muscle tumour by CD31, smooth muscle actin and desmin.  100
anonymous Benign spindle cell tumor: differential diagnoses include myofibroma and solitary fibrous tumor, to be differentiated by CD34 and actin immunostaining nil  80
anonymous Vasoformative tumour DDx: hemangiopericytoma, haemangioendothelioma, solitary fibrous tumour, cellular hemangioma (100% probability) nil  80
anonymous Differential diagnosese: 1. Epithelioid haemangioendothelioma (70%) 2. Solitary fibrous tumour (30%) Perform immunostains for differentiation: Epithelioid haemangioendothelioma positive for factor VIII, CD31 and CD34; SFT positive for CD34 only.  60
anonymous Solitary fibrous tumour (100%). Immunohistochemical stain for CD34 and CD99.  100