Qap (Anatomical Pathology) 

QAP Peer Review

AP150
Case History: F80 Dysphagia. Esophagus biopsy
Intended diagnosis: Malignant melanoma of esophagus. Contributed by:JKCC
Code Diagnosis Comment Score
anonymous Malignant melanoma (100%) Consistent with esophageal primary.  100
anonymous Malignant melanoma (100%) To be confirmed by immunohistochemical study. The tumour cells will be positive for HMB-45 and S100.  100
anonymous Malignant melanoma. 100% nil  100
anonymous Malignant melanoma Confirm by immunostaining for S100, MelanA.  100
anonymous MALIGNANT MELANOMA. 100% The presence of junctional atypical melanocytic proliferation favors a primary esophageal melanoma. However, since metastases are much more common, a cutaneous primary should be excluded clinically.  100
anonymous Malignant melanoma. (100%) Confirm by performing S100 protein, HMB45 and/or Melan A stains which will be positive.  100
anonymous Esophagus biopsy - Primary malignant melanoma of esophagus 100% The junctional change so spotted in this biopsy indicates a primary origin rather than being a metastatic lesion.  100
anonymous Malignant melanoma (100%) To be confirmed with immuhohistochemical studies. Melanoma tumour cells are S100 and HMB45 positive.  100
anonymous Malignant melanoma 100% nil  100
anonymous MALIGNANT MELANOMA (100%) nil  100
anonymous Malignant melanoma (100%) nil  100
anonymous Poorly-differentiated squamous carcinoma 50% Undifferentiated carcinoma 50% nil  50
anonymous Malignant melanoma (100%) Immunostain for HMB45 to confirm the diagnosis of malignant melanoma  100
anonymous malignant melanoma, 100% Correlate clinically to rule out metastatic melanoma  100