Code |
Diagnosis |
Comment |
Score |
anonymous |
Progressive multifocal leukoencephalopathy (PML) (100%)
|
Polyomavirus particles can be identified on electron microscopy or by in-situ hybridization. Also perform immunostain to exclude coexisting toxoplasmosis.
|
100 |
anonymous |
Metastatic carcinoma
|
nil
|
0 |
anonymous |
Progressive multifocal leukoencephalopathy
|
Correlate with microbiology investigations. Diagnosis of JC viral infection is normally confirmed with CSF PCR.
|
100 |
anonymous |
demyelinating disease, compatible with progressive multifocal leukoencephalopathy
|
nil
|
100 |
anonymous |
Consistent with PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY. 100%
|
Diagnosis to be confirmed by immunostains, ISH or EM for JC virus and SV40 virus. Less likely ddx of herpes encephalitis excluded by
immunostains or ISH. Remote ddx of cryptococcus excluded by mucicarmine stain. Radiation induced necrosis also a remote ddx after exclusion of infection.
|
100 |
anonymous |
Progressive multifocal leukoencephalopathy.(100%)
|
nil
|
100 |
anonymous |
Brain - Progressive multifocal leukoencephalopathy 100%
|
Scattered oligodendroglial cells bearing nuclear changes, compatible with JC virus infection
|
100 |
anonymous |
Consistent with post-irradiation effect and demyelination.
|
nil
|
80 |
anonymous |
Demyelinating disease, 100%, consisting with Progressive multifocal leukoencephalopathy
|
nil
|
100 |
anonymous |
Progressive multifocal leukoencephalopathy with presence of viral inclusions consistent with JC papova virus.
|
nil
|
100 |
anonymous |
Radiation change
|
nil
|
50 |
anonymous |
Demyelination with atypical cells, suggestive of progressive multifocal leukoencephalopathy
|
1. Suggest immunostaining for JC virus
2. Differential diagnoses are demyelination as a paraneoplastic syndrome, and radionecrosis. Need to correlate with history of radiation and exact site of lesions.
|
100 |
anonymous |
Progressive multifocal leukoencephalopathy (100%)
|
Clinical and radiologic correlation to differentiate from radionecrosis.
|
100 |
anonymous |
Brain: Progressive multifocal leukoencaphalopathy, perform PAS, Ziehl Neelsen and Grocott stains to rule out infective lesions like Whipple’s disease, TB, and fungal infection.
(100% probability)
|
nil
|
100 |
anonymous |
Subacute hemorrhagic infarction related to irradiation 100%
|
To exclude infective cause by special stains: Grocott and ZN.
|
50 |
anonymous |
Progressive multifocal leukoencephalopathy
|
to be confirmed with immunostain for JC virus
|
100 |