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| Code | Diagnosis | Comment | Score |
| anonymous | Malignant melanoma (100%) | The tumour cells are positive for S100, HMB45 and melan A. | 20 |
| anonymous | Alveolar rhabdomyosarcoma (50%), melamoma(50%) | nil | 50 |
| anonymous | Sarcoma, NOS. Favour rhabdomyosarcoma. | A panel of immunostains should be performed. Positivity for myogenic markers (myogenin, desmin) would confirm rhabdomyosarcoma. Positive S-100 protein may suggest MPNST, and malignant melanoma if it also stains with HMB45. | 100 |
| anonymous | Malignant tumor, favor melanoma (90%), olfactory neuroblastoma (10%). | Confirm with immunohistochemistry: HMB45, MelanA positive in melanoma; chromogranin, synaptophysin positive in olfactory neuroblastoma. | 20 |
| anonymous | Olfactory neuroblastoma. 100% | NSE+, synaptophysin+, S100 focal+. Remote ddx: alveolar rhabdomyosarcoma, muscle markers+. | 40 |
| anonymous | Malignant neoplasm. Rhabdomyosarcoma, especially alveolar rhabdomyosarcoma, has to be considered/excluded.(100%) | Do myogenin stain to confirm diagnosis. Other DDx includes other malignant small round cell tumor e.g. olfactory neuroblastoma, melanoma, sinonasal undifferentiated carcinoma, rhabdoid tumor, etc. | 100 |
| anonymous | NOSE mass - RHABDOMYOSARCOMA 100% | nil | 100 |
| anonymous | Malignant neoplasm ddx: rhabdomyosarcoma (70%),olfactory neuroblastoma (30%) | immunostain: desmin, myoglobin, myogenin, NSE, synaptophysin, chromogranin, neurofilament, S-100 protein | 100 |
| anonymous | Malignant small round cell tumour 100% DDX: olfactory neuroblastoma, sinonasal undifferentiated carcinoma, embryonal rhabdomyosarcoma | Suggest immunohistochemical study i.e. neuron-specific enolase, S-100, chromogranin, desmin, myosin for further delineation. | 63 |
| anonymous | Malignant tumor. Differential diagnosis: 1. Olfactory neuroblastoma. 2. Malignant melanoma. 3. Undifferentiated sinonasal carcinoma. | Need IHC - CK, S-100, HMB45, Melan-A, Synaptophysin, Chromogranin A. | 20 |
| anonymous | Malignant Tumour | Differential diagnoses include osteosarcoma (50%), sinonasal undifferentiated carcinoma (30%), rhabdomyosarcoma (10%) and olfactory neuroblastoma (10%). Immunohistochemical stains for cytokeratin, muscle markers (actin, desmin, myoD1), neural markers (synaptophysin) are suggested to narrow the differential diagnoses. In case of osterosarcoma, history of prior irradiation should be sought (e.g. for NPC). | 40 |
| anonymous | Favour melanoma | Differential diagnoses are sinonasal undifferentiated carcinoma and olfactory neuroblastoma. Suggest immunohistochemical study to exclude - melanoma positive for S100 and HMB45, SNUC for cytokeratins and olfactory neuroblastoma for synaptophysin | 20 |
| anonymous | DDX: rhabdomyosarcoma, neuroendocrine carcinoma and malignant melanoma. Perform desmin, myoD1, smooth muscle actin, S100, HMB45, epithelial markers and neuroendocrine markers. Probability: 100% | nil | 63 |
| anonymous | Alveslar rhabdomyosarcoma. 90% | MyoD1+, Negative NSE/NF to exclude neuroblastoma. | 100 |
| anonymous | Malignant tumor, Differential diagnosis includes rhabdomyosarcomoma (50%), olfactory neuroblastoma (30%), poorly differentiated carcinoma (10%), melanoma (5%), lymphoma (5%) | Immunohistochemical staining for desmin, myoglobin, myo D1, myogenin, AE1/AE3, NSE, synaptophysin, neurofilament, LCA, S-100, HMB-45. | 80 |