Qap (Anatomical Pathology) 

QAP Peer Review

AP314
Case History: F/56 Left jugular mass
Intended diagnosis: Infarcted paraganglioma post embolization treatment. Contributed by:PC
Code Diagnosis Comment Score
anonymous Infarcted paraganglioma with foreign-body induced thrombosis (100%) confirm with immunostaining for synaptophysin.  100
anonymous Foreign body granulomatous reaction to cosmetic filler nil  50
anonymous Foreign body reaction and infarction, consistent with embolization effect. Residual nests of cells suspicious of residual paraganglioma, to perform immunostaining for chromogranin and synaptophysin to confirm. nil  100
anonymous Infarcted paraganglioma due to pre-operative embolization 100% Confirm diagnosis by immunohistochemical studies for S100 and synaptophysin (positive in residual tumor cells).  100
anonymous Paraganglioma with pre-operative embolisation. Confirm by synaptophysin, chromograinin and S100(sustenticular cells). Differential is vascular tumors which should be positive for CD31 and CD34. Sampling for more viable areas.  100
anonymous Paraganglioma (post-therapeutic embolization) (100%) nil  100
anonymous Left jugular mass - Paraganglioma with post embolization changes 100% nil  100
anonymous Foreign body present, suggestive of history of surgical intervention or embolisation Suggest correlate with clinical history of surgical intervention or embolisation.  50
anonymous Paraganglioma 100% nil  90
anonymous Organizing hematoma -Thromboembolism with presence of foreign body material -Polyvinyl alcohol (PVA). nil  50
anonymous JUGULAR MASS:- ORGANIZED THROMBUS, with embolization material seen; atypical epithelioid cells seen, pre-existing paraganglioma cannot be excluded. nil  70
anonymous Infarcted paraganglioma nil  100
anonymous Paraganglioma with effects of embolization. (100%) nil  100
anonymous paraganglioma with extensive infarction due to embolization (100%) correlate with clinical history and perform immunostaining (synaptophysin, S100)  100
anonymous FOREIGN BODY (probable gel foam) with fibrosis and necrosis. Focal cellular area with packeting pattern, need to exclude residual TUMOR area. Perform S100 to exclude paraganglioma. Need history correlation and more sections. (100% probability) nil  90
anonymous Thromobus with foreign material nil  50
anonymous Inflammatory reaction to foreign body (nonbiodegradable soft tissue filler) 100% nil  50
anonymous Jugulotympanic paraganglioma (post embolization) nil  100