Qap (Anatomical Pathology) 

QAP Peer Review

AP247
Case History: M/47, Liver 6 cm mass
Intended diagnosis: Inflammatory pseudotumor, IgG4-related.. Contributed by:MST
Code Diagnosis Comment Score
anonymous Inflammatory pseudotumour, perform IgG4 immunostain for possibility of IgG4-related sclerosing disease. (100%) nil  100
anonymous Inflammatory pseudotumour/IgG4 related sclerosing disease nil  100
anonymous IgG4 related sclerosing disease Confirm with immunostains IgG and IgG4.  100
anonymous Inflammatory pseudotumor, compatible with IgG4-related sclerosing lesion. Immunohistochemical stain for IgG4  100
anonymous INFLAMMATORY PSEUDOTUMOR consistent with IgG4-related sclerosing disease. 100% Confirm by IgG4 immunostain.  100
anonymous IgG4-related sclerosing cholangitis/hepatic inflammatory pseudotumor.(100%) Do IgG and IgG4 stain. Correlate with clinical findings.  100
anonymous IgG4-related sclerosing cholangitis 100% Require confirmation by immunostaining with IgG4 and IgG and assess their ratio  95
anonymous Consistent with post-treatment effect (e.g. chemotherapy), with cirrhosis in the background. Need clinical correlation.  50
anonymous Inflammatory pseudotumour 70% Epithelioid haemangioendothelioma 30% nil  70
anonymous Extensive fibrosclerosing lesion with periductular lymphoplasmacytic infiltrate, suggestive of Autoimmune process or Primary sclerosing cholangitis-like process. Maybe superimposed on a massive hepatocytes loss (previous fulminant hepatitis?) nil  90
anonymous Inflammatory pseudotumor nil  100
anonymous Inflammatory fibrosing/sclerosing process Differential diagnoses include IgG4-related sclerosing disease (confirmed by IgG4 and IgG immunostaining) and inflammatory pseudotumor-group of diseases.  100
anonymous inflammatory fibrosclerosing lesion with obliterative phlebitis, favor inflammatory pseudotumour (100%) Clinical correlation and immunostaining for IgG-4 to exclude underlying IgG-4 related disease.  100
anonymous Liver: Inflammatory pseudotumour, perform CD21&CD35 to exclude follicular dendritic cell tumour (100% probability) nil  100
anonymous Inflammatory pseudotumor 100% nil  100
anonymous Inflammatory pseudotumor To perform IgG4 and IgG to see if it is a IgG4-related sclerosing disease.  100