Code |
Diagnosis |
Comment |
Score |
anonymous |
Choriocarcinoma (100%), with intratubular germ cell neoplasia
|
Further sampling to exclude other germ cell tumour components.
|
100 |
anonymous |
Testis: Embryonal carcinoma with intratubular germ cell neoplasia
|
nil
|
60 |
anonymous |
Germ cell tumour, mixed - with choriocarcinoma and possible embryonal carcinoma element (100%).
|
Need to sample extensively, embed all of the tumour to look for other possible germ cell element etc.
The surrounding testis shows features of severe atrophy and this raises the suspicion of a maldescended testis (is the other testis normal?). In addition there are changes of intratubular germ cell neoplasia, unclassified type (IGCNU) adjacent to the tumour. Cytokeratins, CD30, AFP, HCG etc to confirm embryonal carcinoma and other possible choriocarcinomatous or yolk sac elements.
Immunohistochemistry for PLAP, CD117(c-kit) to confirm IGCNU.
|
95 |
anonymous |
Choriocarcinoma; intratubular germ cell neoplasia.
|
Suggest thorough sampling to look for other germ cell tumor components.
|
100 |
anonymous |
Choriocarcinoma 100%
|
Sampling to look for other germ cell components.
Tumor cells will be highlighted by HCG stain.
|
95 |
anonymous |
Choriocarcinoma. (100%)
|
nil
|
95 |
anonymous |
Testis - Choriocarcinoma 100%
|
nil
|
95 |
anonymous |
Choriocarcinoma (100%)
|
Need extensive sampling to look for other germ cell tumours
|
95 |
anonymous |
Choriocarcinoma 100%
|
nil
|
95 |
anonymous |
Choriocarcinoma in testis with sign of atrophy and hyperplasia of rete testis with intratubular germ cell neoplasia.
|
nil
|
100 |
anonymous |
Left testis for section - CHORIOCARCINOMA (W.H.O.)(malignant teratoma trophoblastic, B.T.T.P.), no other germ cell component, background atrophic seminiferous tubule, cannot rule out undescended testis, no intratubular germ cell neoplasia.
|
The diagnosis can be confirmed by immunohistochemical staining for HCG.
|
95 |
anonymous |
Germ cell tumor: mainly choriocarcinoma
|
There are also small components of intratubular germ cell neoplasia and pagetoid tumor spread in rete testis. Immunostaining (HCG and PlAP) may be performed for delineation of different components of germ cell tumor.
|
100 |
anonymous |
Choriocarcinoma with intratubular germ cell neoplasia in rete testis 100%
|
nil
|
100 |
anonymous |
Choriocarcinoma (100%)
|
Perform hCG stain for confirmation; sample more blocks to look for other germ cell component.
|
95 |
anonymous |
Choriocarcinoma with intratubular germ cell neoplasia
|
More sampling to exclude mixed germ cell tumour.
|
100 |