Code |
Diagnosis |
Comment |
Score |
anonymous |
Autoimmune liver disease (autoimmune cholangitis 80%, autoimmune hepatitis or overlap syndrome 20%)
|
Please correlate clinically with scoring system for exact classification.
Liver biopsy cores show preserved lobular architecture with portal tract expansion by moderate portal inflammatory infiltrate including lymphocytes and plasma cells. Piecemeal necrosis is mild. Bile duct damage is seen. No granuloma is found. Lobular activity is mild. No bridging fibrosis, cirrhosis, rosetting or multinucleated giant cell formation is seen.
|
90 |
anonymous |
Autoimmune cholangitis (100%)
|
nil
|
100 |
anonymous |
Liver: morphologically consistent with Primary biliary cirrhosis, second stage, combining the clinical data: ANF 1:1280, AMA –ve, consistent with autoimmune cholangitis.
|
If responses to low-dose steroids, a define diagnosis can make.
|
100 |
anonymous |
Autoimmune liver disease (autoimmune cholangiopathy, probably with an element of autoimmune hepatitis as suggested by biochemical findings). 100%
|
nil
|
100 |
anonymous |
Autoimmune hepatitis and cholangiopathy
|
These are overlapping autoimmune syndromes.
|
90 |
anonymous |
AUTOIMMUNE CHOLANGITIS. 100%
|
nil
|
100 |
anonymous |
Autoimmune cholangiopathy.(100%)
|
nil
|
100 |
anonymous |
Liver biopsy - autoimmune hepatitis with overlap syndromes 80%
Liver biopsy - autoimmune hepatitis 20%
|
Overlap with primary biliary cirrhosis (currently AMA-ve).
Granulomas in parenchyma also raised possibility of drug-related hepatitis
|
70 |
anonymous |
Autoimmune cholangiopathy, 100%
|
Need to perform stains such as Masson Trichrome or Chromotrope-aniline blue to look for fibrosis. Clinical correlation also in particular to see the profile of liver function test is necessary. A persistent elevated ALT/AST should raise the possbility of autoimmune hepatitis + autoimmune cholangiopathy (overlap syndrome). Changes secondary to drug reaction should also be excluded.
|
100 |
anonymous |
autoimmune hepatitis
|
nil
|
30 |
anonymous |
Hepatitis granulomata -
Primary biliary cirrhosis?
Autoimmune hepatitis?
|
Ziehl-Neelsen and Grocott stain to exclude infectious cause.
|
50 |
anonymous |
Autoimmune Cholangitis (100%)
|
nil
|
100 |
anonymous |
Active chronic hepatitis
Favour PBC 75%
|
Need special stains for copper and CAP
Serology for AMA, viral hepatitis
|
70 |
anonymous |
autoimmune cholangitis 100%
|
nil
|
100 |
anonymous |
Overlap syndrome autoimmune hepatitis/primary biliary cirrhosis
|
nil
|
90 |
anonymous |
Granulomatous and periportal hepatitis, consistent with autoimmune cholangitis (or AMA negative Primary biliary cirrhosis). Probability: 100%
|
Nil
|
100 |
anonymous |
Granulomatous inflammation 100%
|
Differential diagnoses include primary biliary cirrhosis and autoimmune hepatitis. Drug induced hepatitis is also a possibility. Special stains for acid fast bacilli and fungal organisms have to be performed although infective causes are unlikely. Clinical correlation is necessary.
|
50 |
anonymous |
autoimmune cholangitis, stage 1-2
|
nil
|
100 |