Qap (Anatomical Pathology) 

QAP Peer Review

AP133
Case History: F/12, Oral mass detected during molar extraction.
Intended diagnosis: Alveolar rhabdomyosarcoma. Contributed by:FML
Code Diagnosis Comment Score
anonymous Rhabdomyosarcoma (100%) Alveolar subtype is favoured. Advise immunostains for muscle markers including myogenin.  95
anonymous Alveolar rhabdomyosarcoma, 100% To confirm by immunohistochemistry, positive for myoglobin or myogenin.  100
anonymous Alveolar rhabdomyosarcoma 100% To be confirmed by immunohistochemical stains for muscle markers, and molecular study for the characteristic chromosomal translocation.  100
anonymous Rhabdomyosarcoma (alveolar type)(100%) nil  100
anonymous Rhabdomyosarcoma, Alveolar type. Confirm with immunostaining for myoglobin, myogenin, MyoD1 etc.  100
anonymous RHABDOMYOSARCOMA. 100% Suggest sample more blocks to distinguish between alveolar and embryonal type.  90
anonymous Alveolar rhabdomyosarcoma. (100%) nil  100
anonymous Oral cavity-alveolar rhabdomyosarcoma 100% nil  100
anonymous Rhabdomyosarcoma, embryonal type (100%) nil  85
anonymous Rhabdomyosarcoma 100% Suggest confirmation with immunohistochemical staining ,i.e. desmin, myoglobin  90
anonymous Alveolar Rhabdomyosarcoma. 100% nil  100
anonymous Alveolar rhabdomyosarcoma (100%) Foetal rhabdomyoma has been considered, but the alveolar pattern, presence of cytological atypia and poor circumscription favour alveolar rhabdomyosarcoma. For confirmation, the latter shows the distinctive t(2,12) chromosomal translocation.  100
anonymous Fetal rhabdomyoma, intermediate type nil  50
anonymous Embryonal rhabdomyosarcoma. Probability : 100% nil  85
anonymous Alveolar rhabdomyosarcoma 100% nil  100
anonymous Alveolar rhabdomyosarcoma (100%) nil  100