Code |
Diagnosis |
Comment |
Score |
anonymous |
Atypical teratoid/rhabdoid tumour (100%)
|
Immunohistochemically, tumour cells are positive for EMA, vimentin, SMA, sometimes express GFAP and neurofilament. Cytogenetic analysis will show monosomy or deletion of chromosome 22.
|
100 |
anonymous |
AT/RT(Atypical teratoid/rhabdoid tumor)
|
nil
|
100 |
anonymous |
Anaplastic ependymoma
|
Differential diagnosis: embryonal tumour including atypical teratoid rhabdoid tumour, supratentorial PNET and ependymoblastoma.
Immunostains with GFAP, EMA and INI-1.
|
80 |
anonymous |
Atypical Teratoid/rhabdoid tumor
|
Immunostaining for INI1 (loss of staining)
Genomic study for INI1 gene delection
|
100 |
anonymous |
EPENDYMOMA. 100%
|
CONFIRM BY GFAP positivity.
The less likely differential is atypical teratoid/rhabdoid tumor which will show loss of nuclear staining for INI-1.
|
80 |
anonymous |
Atypical teratoid/rhabdoid tumor. 100%
|
Do INI1 which will show loss of nuclear staining.
|
100 |
anonymous |
DDx: Primitive neuroectodermal tumour (40%), Atypical teratoid rhabdoid tumour (40%), Malignant Ependymoma (20%)
|
Require ancillary studies (immunostaining, cytogenetics, molecular studies) for definitive tumour typing
|
80 |
anonymous |
Malignant high grade tumour, favour anaplastic ependymoma (80%) with differential diagnosis include primitive neuroectodermal tumour (PNET) (20%)
|
nil
|
50 |
anonymous |
atypical teratoid/rhabdoid tumour
|
nil
|
100 |
anonymous |
Primary malignant tumor, differential diagnosis: (1) Anaplastic ependymoma; (2) Atypical teratoid/ rhabdoid tumor.
|
Immunohistochemistry: SMA, EMA, GFAP.
|
80 |
anonymous |
Ependymoma
|
nil
|
50 |
anonymous |
Anaplastic ependymoma (WHO grade 3)
|
nil
|
50 |
anonymous |
Anaplastic ependymoma (90%), atypical teratoid/rhabdoid tumour (10%).
|
Immunostaining for GFAP, EMA will be helpful for tumour typing, and Ki67 to establish the proliferative index.
|
80 |
anonymous |
Anaplastic ependymoma, DDX: Atyical teratoid/ Rhabdoid tumour, take more blocks for other component (100% Probability).
|
nil
|
80 |
anonymous |
Malignant tumor (100%), differential diagnoses include atypical teratoid/rhabdoid tumor (50%) and primitive neuroectodermal tumor (50%).
|
Perform immunostains including vimentin, EMA, smooth muscle actin, GFAP, CD99, synaptophysin and INI1. There is loss of INI1 expression in atypical teratoid/rhabdoid tumor.
|
90 |
anonymous |
Anaplastic ependymoma
|
nil
|
50 |