Code |
Diagnosis |
Comment |
Score |
anonymous |
Chordoid meningioma (70%), atypical teratoid/rhabdoid tumour (AT/RT)(30%)
|
Chordoid meningioma: EMA+, CK-, S100 variable
Atypical teratoid/rhabdoid tumour: loss of expression of INI 1, EMA+, CK+, GFAP+
|
100 |
anonymous |
Chordoid meningioma
|
nil
|
50 |
anonymous |
1. Rhabdoid meningioma (50%)
2. Atypical teratoid/rhabdoid tumour (30%)
3. Chordoid meningioma (20%)
|
Perform immunohistochemistry for INI-1. If tumour cells are negative for INI-1, the diagnosis will be atypical teratoid/rhabdoid tumour.
|
100 |
anonymous |
Epithelioid hemangioendothelioma 40%
Chordoid meningioma 40%
Atypical teratoid rhabdoid tumor 20%
|
Immunostaining for:
CD31, CD34, ERG - positive in epithelioid hemangioendothelioma
EMA - positive in maningioma
INI1 - lost in atypical teratoid rhabdoid tumor.
|
100 |
anonymous |
Chordoid meningioma, grade 2 (WHO), with brain invasion. 100%
|
Dx can be confirmed by EMA+.
Brain invasion can be confirmed and highlighted by background GFAP stain.
|
50 |
anonymous |
Rhabdoid neoplasm
Atypical teratoid/rhaboid tumor vs Rhabdoid meningioma
|
ATRT is characterized by loss of INI1 stain, while rhabdoid meningioma shows retained nuclear stain of INI1 stain in the tumor cells
|
100 |
anonymous |
Malignant (Ansplastic) Meningioma (WHO Grade III) 100%
|
There are chordoid areas and foci of dubious rhabdoid cell configuration
|
50 |
anonymous |
Atypical teratoid/rhabdoid tumour 50%
Chordoid meningioma WHO G2 50%
|
perform immunostain for INI1 to cofirm ATRT vs meningeal differentiation.
|
100 |
anonymous |
70% chordoid meningioma
30% ATRT (atypical teratoid/rhabdoid tumour)
|
nil
|
100 |
anonymous |
Favoring Atypical Epithelioid Haemangioendothelioma.
Differential diagnosis - Chordoid meningioma.
|
nil
|
50 |
anonymous |
Left temporal tumor:- Myxoid tumour with neoplastic cells having rhabdoid morphology, differential diagnoses including:
1) Meningioma, chordoid/rhabdoid variant, WHO grade III (probability 50%)
2) Atypical teratoid/rhabdoid tumor, WHO grade IV (probability 50%)
|
Definitive diagnosis cannot be made without support of immunohistochemistry:
1) Meningioma, chordoid/rhabdoid variant (WHO grade III)
- confirmed by positive EMA stain
2) Atypical teratoid/rhabdoid tumor (WHO grade IV)
- confirmed by loss of INI-1 by immunostain
|
100 |
anonymous |
Atypical teratoid rhabdoid tumor.
|
nil
|
100 |
anonymous |
Malignant neoplasm with chordoid features, with the differential diagnosis including atypical teratoid/rhabdoid tumour (70%) and chordoid meningioma (30%).
|
Immunohistochemical staining would be performed, including INI1, EMA and GFAP. INI1 would be negative in atypical teratoid/rhabdoid tumour and positive in chordoid meningioma. For chordoid meningioma the expected pattern is EMA positive, GFAP negative.
|
100 |
anonymous |
atypical teratoid/rhabdoid tumor (100%)
|
nil
|
100 |
anonymous |
Brain ?Malignant neoplasm, differential diagnoses included Chordoid meningioma and Atypical teratoid and rhabdoid tumor, need to perform immunohistochemistry of keratin and molecular study of INI1. (100% probability).
|
nil
|
100 |
anonymous |
Chordoid Meningioma
|
nil
|
50 |
anonymous |
Chordoid meningioma, grade II (WHO) 100%
|
nil
|
50 |
anonymous |
Chordoid meningioma. W.H.O. Grade 2.
|
nil
|
50 |