Qap (Anatomical Pathology) 

QAP Peer Review

AP310
Case History: F/28. Pregnance 11 week by date. ? Missed abortion on ultrasound. Uterine curetting.
Intended diagnosis: Complete hydatidiform mole. Contributed by:JKCC
Code Diagnosis Comment Score
anonymous Complete Hydatidiform Mole (100%) Immunostaining for p57 is negative in the cytotrophoblasts and villous mesenchyme  100
anonymous Early complete mole perform immunostaining of P57 antibody to confirm  100
anonymous Complete hydatidiform mole nil  100
anonymous Hydatidiform molar pregnancy, favor complete mole Perform immunohistochemistry for p57 (lack of staining in villous stromal cells and cytotrophoblasts in complete mole).  100
anonymous Complete mole 70%. Partial mole 30%. Distinction can be by flow cytometry. Complete mole is diploid. Partial mole is triploid. Also by IHC for p57.  100
anonymous Molar pregnancy (100%) The features are in favor of complete mole. Immunohistohistochemistry of p57 to look for the loss of stain in cytotrophoblasts and villous mesenchymal cells to confirm the diagnosis of complete mole.  100
anonymous Uterine curetting - Complete hydatidiform mole 100% To do immunostain p57 and to correlate with serial clinical serology (beta HCG) data  100
anonymous Molar pregnancy, favour complete mole (100%) Immunostain for p57 protein to confirm the diagnosis (negative or markedly decreased in complete mole)  100
anonymous Complete hydatidiform mole. 100% nil  100
anonymous Hydatidiform mole, favoring Complete. Immunostain for P57 for demonstration of absence of staining in the cytotrophoblast and villous mesenchyme.  100
anonymous ENDOMETRIUM, curetting - COMPLETE HYDATIDIFORM MOLE nil  100
anonymous Hydatidiform mole, in favor of complete mole. (Please see comment) In order to differentiate partial and complete hydatidiform mole, all embedded the tissue submitted for examination to look for normal chorionic villi, nucleated red cells as well as fetal part which is indicative for partial mole. Immunohistochemical stain for p57 is negative in the villous stromal cells in complete mole and positive in villous stromal cells in partial mole.  100
anonymous Complete hydatidiform mole. (100%) Immunohistochemical staining for p57 for confirmation.  100
anonymous complete hydatidiform mole (100%) perform immunostaining for p57 for confirmation (negative in complete mole)  100
anonymous COMPLETE HYDATIDIFORM MOLE (100% probability) nil  100
anonymous Partial Hydatidiform mole nil  80
anonymous Partial hydatidiform mole 100% placental alkaline phosphatase  80
anonymous Complete mole (100%) nil  100