Code |
Diagnosis |
Comment |
Score |
anonymous |
Extramammary Paget's disease (100%)
|
nil
|
100 |
anonymous |
Extramammary Paget's disease. 100%
|
To be confirmed by immunostains for cytokeratin; S100 protein and HMB45 to exclude melanoma
|
100 |
anonymous |
Extramammary Paget's disease. 100%
|
nil
|
100 |
anonymous |
Penile SKIN : EXTRAMAMMARY PAGET'S DISEASE (100%)
|
Stromal invasion is suspected focally. Deeper sections are advised for confirmation.
In penile skin, the lesion may be purely intraepidermal or associated with an underlying adenocarcinoma.
|
100 |
anonymous |
Extramammary Paget's Disease (70%)
Melanoma (30%)
|
The following would be performed:
Mucin stains, immunostains for carcinoembryonic antigen and cytokeratins (would be positive in Paget's disease but negative in melanoma) as well as immunostains for S100 and HMB45 (which would be positive in melanoma but negative in Paget's disease)
|
100 |
anonymous |
Extramammary Paget's disease
|
Deeper sections to exclude invasion;
To exclude associated tumor including skin adnexal and visceral malignancy.
|
100 |
anonymous |
Extramammary Paget's disease. 100%
|
The diagnosis can be confirmed by positivity for CAM5.2 and negativity for S100,ie excluding melanoma.
|
100 |
anonymous |
Paget's disease
|
nil
|
95 |
anonymous |
Extramammary Paget's Disease 100%
|
Do immunostains: CEA to confirm and S-100 protein to exclude Pagetoid melanoma
|
100 |
anonymous |
Paget's disease, extramammary (100%)
|
nil
|
100 |
anonymous |
Extramammary Paget's Disease 100%
|
nil
|
100 |
anonymous |
Paget's disease 100%
|
nil
|
95 |
anonymous |
Extramammary Paget's Disease 100%
|
nil
|
100 |
anonymous |
Extramammary Paget's disease 100%
|
It is prudent to confirm the diagnosis by immunohistochemical stains: the tumour cells should be postive for cytokeratin and negative for HMB45.
|
100 |
anonymous |
Extramammary Paget's disease
100%
|
nil
|
100 |
anonymous |
Extramammary paget's disease, suspicious of early invasion, no underlying carcinoma. (100%)
|
Have to exclude underlying carcinoma, and carcinoma in adjacent sites.
|
100 |
anonymous |
Extramammary Paget's disease 100%
|
nil
|
100 |
anonymous |
extramammary Paget's disease
|
nil
|
100 |