Qap (Anatomical Pathology) 

Case: AP287
Contributor's Comment: EED is one of the so called ¡¥chronic leucocytoclastic vasculitis¡¦. It may develop in any age but usually adult of 3rd to 6th decade. They are usually multiple with roughly symmetrical distribution, mostly over extensor aspect of joints, esp hands, elbows or knees. Early lesion may resemble leucocytoclastic vasculitis with fibrinoid necrosis of vessel walls, presence of nuclear dusts and minimal fibrosis. However, in well-developed lesion, fibrosis, esp patterned fibrosis, will predominate with nuclear dusts. Fibrinoid necrosis of vessel wall will not be apparent at this stage. Early treatment may include dapsone. Advanced stage is usually treated by excision.