QAP-AP105

Granulomatous lesions of the prostate are many, and the most commonly encountered or recognized by relatively distinctive features include:

• the so-called non-specific granulomatous prostatitis
• post-transurethral resection granulomatous inflammation
• post-BCG therapy
• infectious
• allergic (eosinophilic)
• malakoplakia
• others

Case AP105 is a rather typical example of a post-TURP granulomatous inflammation, showing necrobiotic nodules surrounded by epithelioid histiocytes with nuclear palisading, and multinucleated giant cells. Most participants got it right, but for a few 5 points were deducted for reporting simply "granulomatous prostatitis" without further specification. "Granulomatous prostatitis" refers to the so-called non-specific granulomatous prostatitis, a lesion usually centered around the ducts, unrelated to surgical procedure, presumably due to prostatic concretions or obstruction, and reaction to rupture of ducts, but clinically important as the condition may mimic prostatic carcinoma.